Selected publications

Recent articles

Peer-reviewed research in translational oncovirology, molecular biomarkers and virus-associated carcinogenesis.

2026

MMTV-like Viruses and Human Breast Cancer: Evidence for Causality

Current Issues in Molecular Biology, 48(2), 157

Acevedo, Mónica L., Aguayo, Francisco, Osorio, Julio C., Ardiles, Luis N., Calaf, Gloria M.

Review of the evidence linking MMTV-like viruses to human breast cancer.

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2024

Epstein-Barr Virus BARF1 Is Expressed in Lung Cancer and Is Associated with Cancer Progression

Cells, 13(18), 1578

Osorio, Julio C., Armijo, Alvaro, Carvajal, Francisco J., Corvalán, Alejandro H., Castillo, Andrés, Fuentes-Pananá, Ezequiel M., Moreno-León, Carolina, Romero, Carmen, Aguayo, Francisco

Analysis of 158 Chilean lung carcinomas: detects the EBV oncoprotein BARF1 and shows its association with lung cancer progression.

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2024

SLC7A11 Expression Is Up-Regulated in HPV- and Tobacco-Associated Lung Cancer

International Journal of Molecular Sciences, 25, 13248

Osorio, Julio C., Andrade-Madrigal, Cristian, Gheit, Tarik, Corvalán, Alejandro H., Aguayo, Francisco

Analysis of 204 lung cancer cases in Chile: HPV16 is found in 4% of tumors and is associated with higher SLC7A11 expression and poorer survival.

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2023

Interaction between Cigarette Smoke and HPV16 E6/E7 Oncoproteins to Induce SOD2 Expression and DNA Damage in Head and Neck Cancer

International Journal of Molecular Sciences

Carrillo-Beltrán, Diego, Osorio, Julio C., Blanco, Rancés, Oliva, Carolina, Boccardo, Enrique, Aguayo, Francisco

Shows that cigarette smoke and HPV16 oncoproteins act synergistically, increasing DNA damage in head and neck cells.

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2022

High-Risk Human Papillomavirus Infection in Lung Cancer: Mechanisms and Perspectives

Biology, 11(12), 1691

Osorio, Julio C., Candia-Escobar, Felipe, Corvalán, Alejandro H., Calaf, Gloria M., Aguayo, Francisco

Review of the epidemiological and experimental evidence on the role of high-risk HPV in lung cancer, in smokers and non-smokers.

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2022

Epstein–Barr Virus Infection in Lung Cancer: Insights and Perspectives

Pathogens, 11(2), 132

Osorio, Julio C., Blanco, Rancés, Corvalán, Alejandro H., Muñoz, Juan P., Calaf, Gloria M., Aguayo, Francisco

Review of the heterogeneous detection of EBV in lung cancer and the possible mechanisms of viral carcinogenesis.

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